.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G01A_AntiinfectivesAndAntisepticsExclCombinationsWith.G01AA10_Clindamycin.Clindamycin_1 .Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G01A_AntiinfectivesAndAntisepticsExclCombinationsWith.G01AA10_Clindamycin.Clindamycin_1| name: | Clindamycin_1 |
| ATC code: | G01AA10_1 | route: | intravenous |
| n-compartments | 2 |
Clindamycin is a broad-spectrum lincosamide antibiotic, effective against Gram-positive cocci and anaerobic bacteria. Approved and used in treatment of infections such as MRSA, dental infections, and pelvic inflammatory disease.
Pharmacokinetics after intravenous administration in healthy adults (single 600 mg IV dose).
Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866
Bouazza, N, et al., & Tréluyer, JM (2012). Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. British journal of clinical pharmacology 74(6) 971–977. DOI:10.1111/j.1365-2125.2012.04292.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22486719
Smith, MJ, et al., & Watt, K (2017). Pharmacokinetics of Clindamycin in Obese and Nonobese Children. Antimicrobial agents and chemotherapy 61(4) –. DOI:10.1128/AAC.02014-16 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28137820