name: | Oxiconazole |
ATC code: | G01AF17 | route: | topical |
n-compartments | 1 |
Oxiconazole is an imidazole-class antifungal agent, primarily used topically to treat skin infections such as athlete's foot, ringworm, and jock itch caused by dermatophytes and yeasts. It is available as a cream and lotion but not typically approved for systemic or oral administration.
No published human pharmacokinetic models or parameters for systemic (oral, IV) oxiconazole administration exist. As oxiconazole is almost exclusively used as a topical preparation, systemic absorption is minimal. Parameters below are estimates based on general properties of imidazole antifungals when systemically administered, for a hypothetical adult subject.