name: | Ciclopirox |
ATC code: | G01AX12 | route: | topical |
n-compartments | 1 |
Ciclopirox is a synthetic antifungal agent used mainly in topical formulations to treat dermatophytoses, candidiasis, and seborrheic dermatitis. It is not typically used systemically and is approved for topical use in various countries.
Estimated pharmacokinetic parameters for topical application in adults; no published clinical pharmacokinetic studies available for oral, intravenous, or systemic administration.
Gupta, AK, et al., & Foley, KA (2014). Topical therapy for toenail onychomycosis: an evidence-based review. American journal of clinical dermatology 15(6) 489–502. DOI:10.1007/s40257-014-0096-2 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25257931
Hafeez, F, et al., & Maibach, H (2014). Ciclopirox delivery into the human nail plate using novel lipid diffusion enhancers. Drug development and industrial pharmacy 40(6) 838–844. DOI:10.3109/03639045.2013.788016 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23600655