.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G02C_OtherGynecologicals.G02CC01_Ibuprofen.Ibuprofen

Information

name:Ibuprofen
ATC code:G02CC01
route:oral
n-compartments2

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of pain, fever, and inflammation. It is approved and commonly used worldwide for mild to moderate pain, dysmenorrhea, and inflammatory conditions such as arthritis.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers (both sexes) after a single oral dose.

References

  1. Moore, RA, et al., & Straube, S (2015). Effects of food on pharmacokinetics of immediate release oral formulations of aspirin, dipyrone, paracetamol and NSAIDs - a systematic review. British journal of clinical pharmacology 80(3) 381–388. DOI:10.1111/bcp.12628 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25784216

  2. Thigpen, JC, et al., & Harirforoosh, S (2019). Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children. European journal of drug metabolism and pharmacokinetics 44(5) 591–609. DOI:10.1007/s13318-019-00552-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31006834

  3. Sharma, PK, et al., & Narang, A (2003). Pharmacokinetics of oral ibuprofen in premature infants. Journal of clinical pharmacology 43(9) 968–973. DOI:10.1177/0091270003254635 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12971028

Revisions


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