.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G02C_OtherGynecologicals.G02CC02_Naproxen.Naproxen

Information

name:Naproxen
ATC code:G02CC02
route:oral
n-compartments1

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the treatment of pain, inflammation, and fever. It is widely used to manage symptoms associated with arthritis, musculoskeletal disorders, and menstrual pain. Naproxen is an approved and currently marketed medication available over the counter and by prescription.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after single oral administration.

References

  1. Välitalo, P, et al., & Kokki, H (2012). Plasma and cerebrospinal fluid pharmacokinetics of naproxen in children. Journal of clinical pharmacology 52(10) 1516–1526. DOI:10.1177/0091270011418658 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22067196

  2. Mendell, J, et al., & Samama, MM (2013). The effects of the antiplatelet agents, aspirin and naproxen, on pharmacokinetics and pharmacodynamics of the anticoagulant edoxaban, a direct factor Xa inhibitor. Journal of cardiovascular pharmacology 62(2) 212–221. DOI:10.1097/FJC.0b013e3182970991 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23615159

  3. Kubitza, D, et al., & Zuehlsdorf, M (2007). Rivaroxaban (BAY 59-7939)--an oral, direct Factor Xa inhibitor--has no clinically relevant interaction with naproxen. British journal of clinical pharmacology 63(4) 469–476. DOI:10.1111/j.1365-2125.2006.02776.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/17100983

Revisions


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