.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA05_NorethisteroneAndEthinyl.NorethisteroneAndEthinyl .Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA05_NorethisteroneAndEthinyl.NorethisteroneAndEthinyl| name: | NorethisteroneAndEthinylestradiol | |
| ATC code: | G03AA05 | route: | oral |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 60 | L |
| clearance: | 2.5 | L/h |
| other parameters in model implementation | ||
Combination oral contraceptive containing norethisterone (a progestin) and ethinylestradiol (an estrogen), used for birth control. Widely approved and in use as a contraceptive agent worldwide.
Pharmacokinetic parameters estimated for healthy adult females, using typical dose regimens and literature data for individual components. No direct clinical population PK publication reporting a model for the combined preparation (G03AA05) as a unit.
Kiriwat, O, & Fotherby, K (1983). Pharmacokinetics of oral contraceptive steroids after morning or evening administration. Contraception 27(2) 153–160. DOI:10.1016/0010-7824(83)90086-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/6851554