.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA14_NomegestrolAndEstradiol.NomegestrolAndEstradiol .Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA14_NomegestrolAndEstradiol.NomegestrolAndEstradiol| name: | NomegestrolAndEstradiol |
| ATC code: | G03AA14 | route: | oral |
| n-compartments | 1 |
Nomegestrol acetate with estradiol is a combined oral contraceptive used for female contraception. It combines nomegestrol, a progestogen, with estradiol, a naturally occurring estrogen. This combination is approved and marketed in several countries for regular use in birth control.
Estimated pharmacokinetic parameters for healthy adult females following oral administration. No direct published population PK models or detailed compartmental parameters for the combination product found.
Post, TM, et al., & de Greef, R (2016). Prediction of nomegestrol acetate pharmacokinetics in healthy female adolescents and adults by whole-body physiology-based pharmacokinetic modelling and clinical validation. Contraception 93(2) 133–138. DOI:10.1016/j.contraception.2015.08.017 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26365792