.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA18_DrospirenoneAndEstetrol.DrospirenoneAndEstetrol .Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AA18_DrospirenoneAndEstetrol.DrospirenoneAndEstetrol| name: | DrospirenoneAndEstetrol | |
| ATC code: | G03AA18 | route: | oral |
| compartments: | 1 | |
| dosage: | 3 | mg |
| volume of distribution: | 4 | L |
| clearance: | 1.5 | L/h |
| other parameters in model implementation | ||
Drospirenone and estetrol is a combined oral contraceptive containing a progestin (drospirenone) and a natural estrogen (estetrol); it is used for the prevention of pregnancy in women of reproductive age. The product is approved in several countries and marketed primarily under trade names such as Nextstellis and Drovelis.
Pharmacokinetic parameters refer to healthy premenopausal women receiving daily oral doses of 14.2 mg estetrol and 3 mg drospirenone, based on available summary data and regulatory sources.