.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AB05_DesogestrelAndEthinylest.DesogestrelAndEthinylest .Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AB05_DesogestrelAndEthinylest.DesogestrelAndEthinylest| name: | DesogestrelAndEthinylestradiol | |
| ATC code: | G03AB05 | route: | oral |
| compartments: | 2 | |
| dosage: | 0.15 | mg |
| volume of distribution: | 2 | L |
| clearance: | 5 | L/h |
| other parameters in model implementation | ||
Desogestrel and ethinylestradiol is a combined oral contraceptive pill used for the prevention of pregnancy. It consists of desogestrel, a progestin, and ethinylestradiol, an estrogen. This combination is approved and widely used today for hormonal contraception.
Pharmacokinetic parameters estimated for healthy adult women following oral administration of standard contraceptive dose.
Bergink, W, et al., & Qvist, I (1990). Serum pharmacokinetics of orally administered desogestrel and binding of contraceptive progestogens to sex hormone-binding globulin. American journal of obstetrics and gynecology 163(6 Pt 2) 2132–2137. DOI:10.1016/0002-9378(90)90553-j PUBMED:https://pubmed.ncbi.nlm.nih.gov/2147817