.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03A_HormonalContraceptivesForSystemicUse.G03AC08_Etonogestrel.Etonogestrel

Information

name:Etonogestrel
ATC code:G03AC08
route:subdermal
n-compartments1

Etonogestrel is a synthetic progestin used as a hormonal contraceptive. It is the active metabolite of desogestrel and is currently marketed as a subdermal implant (Nexplanon/Implanon) for long-term birth control in women. It is approved and widely used for contraception.

Pharmacokinetics

Pharmacokinetic parameters for healthy women aged 18–40 years receiving the etonogestrel subdermal implant (single 68 mg implant, commonly used contraceptive dose).

References

  1. Clure, C, et al., & Lazorwitz, A (2024). Pilot study of a novel, alternative subdermal scapular insertion site for the etonogestrel contraceptive implant. Contraception 135 110442–None. DOI:10.1016/j.contraception.2024.110442 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38552822

  2. Ali, M, et al., & Hubacher, D (2016). Extended use up to 5 years of the etonogestrel-releasing subdermal contraceptive implant: comparison to levonorgestrel-releasing subdermal implant. Human reproduction (Oxford, England) 31(11) 2491–2498. DOI:10.1093/humrep/dew222 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27671673

Revisions


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