.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03D_Progestogens.G03DA04_Progesterone.Progesterone

Information

name:Progesterone
ATC code:G03DA04
route:oral
n-compartments1

Progesterone is a natural steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis. It is used as a medication primarily for hormone replacement therapy, treatment of menstrual disorders, and as a component of hormonal contraceptives. Progesterone is approved for use today in various oral, vaginal, and injectable forms.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult women after a single oral dose administration of micronized progesterone.

References

  1. Wang, H, et al., & Deng, C (2019). Pharmacokinetics of hard micronized progesterone capsules via vaginal or oral route compared with soft micronized capsules in healthy postmenopausal women: a randomized open-label clinical study. Drug design, development and therapy 13 2475–2482. DOI:10.2147/DDDT.S204624 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31440031

  2. Beumer, JH, & Foldi, J (2023). Pharmacology and pharmacokinetics of elacestrant. Cancer chemotherapy and pharmacology 92(2) 157–163. DOI:10.1007/s00280-023-04550-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37314500

  3. Liu, H, et al., & Schultze-Mosgau, MH (2021). Pharmacokinetics and Safety of the Selective Progesterone Receptor Modulator Vilaprisan in Chinese Healthy Postmenopausal Women. Clinical pharmacology in drug development 10(5) 486–493. DOI:10.1002/cpdd.851 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32716091

Revisions


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