.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G03D_Progestogens.G03DB06_Chlormadinone.Chlormadinone

Information

Chlormadinone is a synthetic progestin hormone related to progesterone, used primarily as an oral contraceptive component and in some countries for treatment of menopausal symptoms or androgen-dependent conditions. Its use has declined and is largely limited to certain regions, with alternatives being more commonly employed.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adult women based on available data and similarities to related progestins, as no definitive, peer-reviewed population pharmacokinetic studies reporting detailed parameters for chlormadinone are accessible.

References

1. Huang, T, et al., & Yang, L (2011). Inhibitory potential of chlormadinone acetate (CMA) on five important UDP-glucuronosyltransferases in human liver. Die Pharmazie 66(3) 212–215. PUBMED:https://pubmed.ncbi.nlm.nih.gov/21553653

Revisions

• 06/2025 initial generated model