.Pharmacolibrary.Drugs.G_GenitoUrinarySystemAndSexHormones.G04B_Urologicals.G04BE01_Alprostadil.Alprostadil

Information

name:Alprostadil
ATC code:G04BE01
route:intracavernosal
n-compartments2

Alprostadil (prostaglandin E1) is a vasodilator and smooth muscle relaxant used mainly for the treatment of erectile dysfunction and to maintain patency of the ductus arteriosus in newborns with congenital heart defects. It is administered by intracavernosal injection, intraurethrally, or by intravenous or intraarterial routes in neonates. Alprostadil is an approved drug and is in current clinical use.

Pharmacokinetics

Healthy adult males following intracavernosal administration.

References

  1. Porst, H, et al., & Sharlip, I (2013). SOP conservative (medical and mechanical) treatment of erectile dysfunction. The journal of sexual medicine 10(1) 130–171. DOI:10.1111/jsm.12023 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23343170

Revisions

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