.Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01B_PosteriorPituitaryLobeHormones.H01BA03_Lypressin.Lypressin .Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01B_PosteriorPituitaryLobeHormones.H01BA03_Lypressin.Lypressin| name: | Lypressin |
| ATC code: | H01BA03 | route: | intranasal |
| n-compartments | 1 |
Lypressin (lysine vasopressin) is a synthetic analogue of the natural antidiuretic hormone vasopressin, previously used to treat diabetes insipidus, particularly central diabetes insipidus. It acts as a replacement for ADH deficiency by promoting water reabsorption in the renal collecting ducts. Lypressin is no longer widely used, having been replaced by desmopressin for this indication.
No peer-reviewed clinical pharmacokinetic studies specifically reporting parameters for lypressin in humans could be identified. The following are estimated pharmacokinetic values based on general vasopressin analogues and known properties.