.Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01B_PosteriorPituitaryLobeHormones.H01BB03_Carbetocin.Carbetocin .Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01B_PosteriorPituitaryLobeHormones.H01BB03_Carbetocin.Carbetocin| name: | Carbetocin |
| ATC code: | H01BB03 | route: | intravenous |
| n-compartments | 2 |
Carbetocin is a synthetic long-acting analogue of oxytocin, used mainly for the prevention of uterine atony and postpartum hemorrhage following delivery by cesarean section. It acts as a uterotonic agent and is approved in various countries for use immediately after childbirth, particularly following cesarean delivery under anesthesia.
Pharmacokinetic parameters reported in healthy postpartum women after intravenous administration of a single 100 mcg dose following cesarean section.
Schramme, AR, et al., & Whitacre, MD (2008). Pharmacokinetics of carbetocin, a long-acting oxytocin analogue, following intravenous administration in horses. Equine veterinary journal 40(7) 658–661. DOI:10.2746/042516408x334343 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19165935