.Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01C_HypothalamicHormones.H01CB01_Somatostatin.Somatostatin .Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H01C_HypothalamicHormones.H01CB01_Somatostatin.Somatostatin| name: | Somatostatin |
| ATC code: | H01CB01 | route: | intravenous |
| n-compartments | 2 |
Somatostatin is a cyclic peptide hormone that inhibits the secretion of several other hormones, such as growth hormone, insulin, and glucagon. It is used therapeutically to control bleeding from esophageal varices and in the management of certain endocrine and gastrointestinal disorders. Due to its very short half-life, somatostatin is generally used only in hospital settings for acute indications. Synthetic analogues (e.g., octreotide) are commonly used instead for chronic therapy.
Pharmacokinetic parameters are mainly derived from studies in healthy adult volunteers following intravenous infusion.
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