.Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H02A_CorticosteroidsForSystemicUsePlain.H02AB01_Betamethasone.Betamethasone .Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H02A_CorticosteroidsForSystemicUsePlain.H02AB01_Betamethasone.Betamethasone| name: | Betamethasone |
| ATC code: | H02AB01 | route: | oral |
| n-compartments | 1 |
Betamethasone is a potent synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties. It is commonly used to treat various conditions such as allergic disorders, skin diseases, rheumatic disorders, and for antenatal fetal lung maturation. Betamethasone is widely approved and used in current clinical practice.
PK parameters reported for healthy adult volunteers after oral administration of betamethasone.
Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(2) 261–272. DOI:10.1007/s10928-020-09730-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/33389521
Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(3) 411–438. DOI:10.1007/s10928-021-09755-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/33954911
Lim, SY, et al., & Heard, CM (2020). Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International journal of pharmaceutics 573 118860–None. DOI:10.1016/j.ijpharm.2019.118860 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31759104