.Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H02A_CorticosteroidsForSystemicUsePlain.H02AB10_Cortisone.Cortisone .Pharmacolibrary.Drugs.H_SystemicHormonalPreparationsExclSexHormonesAndInsulins.H02A_CorticosteroidsForSystemicUsePlain.H02AB10_Cortisone.Cortisone| name: | Cortisone |
| ATC code: | H02AB10 | route: | oral |
| n-compartments | 1 |
Cortisone is a naturally occurring corticosteroid hormone (glucocorticoid) produced by the adrenal cortex. It is used as a replacement therapy for adrenocortical insufficiency (such as Addison's disease) and historically was used for its anti-inflammatory and immunosuppressive properties. Over time, its clinical use has largely been replaced by other synthetic corticosteroids with more favorable pharmacokinetics. It is not commonly used as a first-line therapy today.
Typical pharmacokinetic parameters estimated for an average adult without specific disease conditions, based on general glucocorticoid pharmacology due to limited direct clinical PK data for cortisone.
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