.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01A_Tetracyclines.J01AA01_Demeclocycline.Demeclocycline .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01A_Tetracyclines.J01AA01_Demeclocycline.Demeclocycline| name: | Demeclocycline | |
| ATC code: | J01AA01 | route: | oral |
| compartments: | 1 | |
| dosage: | 150 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 30 | mL/min |
| other parameters in model implementation | ||
Demeclocycline is a tetracycline antibiotic used primarily for the treatment of infections caused by susceptible strains of bacteria, particularly respiratory tract, urinary tract, and skin infections. It has also been historically used to treat syndrome of inappropriate antidiuretic hormone secretion (SIADH). However, demeclocycline's use is limited today due to adverse effects and availability of safer alternatives.
Pharmacokinetic parameters reported in healthy adult volunteers after a single oral dose.