.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01A_Tetracyclines.J01AA03_Chlortetracycline.Chlortetracycline .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01A_Tetracyclines.J01AA03_Chlortetracycline.Chlortetracycline| name: | Chlortetracycline |
| ATC code: | J01AA03 | route: | oral |
| n-compartments | 1 |
Chlortetracycline is a broad-spectrum tetracycline antibiotic, historically used for bacterial infections in humans and animals. It is less commonly used in human medicine today due to resistance and newer alternatives. Its primary use is now in veterinary medicine and as a growth promotant in animal feed.
Estimated pharmacokinetic parameters based on class characteristics and sparse historical data; no direct modern clinical PK study in humans was identified.
Zhang, Y, et al., & Yu, M (2022). Florfenicol/Chlortetracycline Effect on Pharmacodynamic Indices for Mutant Selection of . Microbial drug resistance (Larchmont, N.Y.) 28(7) 832–840. DOI:10.1089/mdr.2022.0008 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35723674
Cazer, CL, et al., & Gröhn, YT (2018). Expanding behavior pattern sensitivity analysis with model selection and survival analysis. BMC veterinary research 14(1) 355–None. DOI:10.1186/s12917-018-1674-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/30453986
Cazer, CL, et al., & Gröhn, YT (2017). Monte Carlo Simulations Suggest Current Chlortetracycline Drug-Residue Based Withdrawal Periods Would Not Control Antimicrobial Resistance Dissemination from Feedlot to Slaughterhouse. Frontiers in microbiology 8 1753–None. DOI:10.3389/fmicb.2017.01753 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29033901