.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CA04_Amoxicillin.Amoxicillin

Information

name:Amoxicillin
ATC code:J01CA04
route:oral
n-compartments1

Amoxicillin is a broad-spectrum, beta-lactam antibiotic from the aminopenicillin class, used to treat a variety of bacterial infections such as respiratory tract infections, urinary tract infections, and otitis media. It is commonly used today and approved for clinical use in many countries.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects after a single oral dose.

References

  1. Keij, FM, et al., & Flint, RB (2023). Oral and Intravenous Amoxicillin Dosing Recommendations in Neonates: A Pooled Population Pharmacokinetic Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 77(11) 1595–1603. DOI:10.1093/cid/ciad432 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37757471

  2. Mellon, G, et al., & Crémieux, AC (2020). Population pharmacokinetics and dosing simulations of amoxicillin in obese adults receiving co-amoxiclav. The Journal of antimicrobial chemotherapy 75(12) 3611–3618. DOI:10.1093/jac/dkaa368 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32888018

  3. Bock, M, et al., & Moser, C (2023). Attainment of Target Antibiotic Levels by Oral Treatment of Left-Sided Infective Endocarditis: A POET Substudy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 77(2) 242–251. DOI:10.1093/cid/ciad168 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36947131

Revisions


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