.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CA11_Mecillinam.Mecillinam_1

Information

Mecillinam is a beta-lactam antibiotic of the penicillin class, specifically an amidinopenicillin, used primarily to treat urinary tract infections caused by Gram-negative bacteria, particularly Escherichia coli. It is approved and is still in clinical use, especially in Scandinavia and some European countries.

Pharmacokinetics

Pharmacokinetic parameters observed in healthy adults after intravenous administration.

References

1. Zayyad, H, et al., & Paul, M (2017). Revival of old antibiotics: needs, the state of evidence and expectations. International journal of antimicrobial agents 49(5) 536–541. DOI:10.1016/j.ijantimicag.2016.11.021 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28162982

Revisions

• 06/2025 initial generated model