.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CA13_Ticarcillin.Ticarcillin

Information

Ticarcillin is a broad-spectrum, semi-synthetic penicillin antibiotic primarily used for the treatment of infections caused by susceptible Gram-negative and some Gram-positive bacteria. It is historically used in the management of serious infections such as those due to Pseudomonas aeruginosa. Ticarcillin is often combined with clavulanic acid to overcome beta-lactamase-mediated resistance. It has largely been replaced by other agents in many therapeutic settings, but may still be used in some hospitals.

Pharmacokinetics

Pharmacokinetics in healthy adult volunteers following intravenous administration.

References

1. Massie, J, & Cranswick, N (2006). Pharmacokinetic profile of once daily intravenous tobramycin in children with cystic fibrosis. Journal of paediatrics and child health 42(10) 601–605. DOI:10.1111/j.1440-1754.2006.00944.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/16972966

Revisions

• 06/2025 initial generated model