.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CE02_Phenoxymethylpenicillin.Phenoxymethylpenicillin .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CE02_Phenoxymethylpenicillin.Phenoxymethylpenicillin| name: | Phenoxymethylpenicillin |
| ATC code: | J01CE02 | route: | oral |
| n-compartments | 1 |
Phenoxymethylpenicillin, also known as penicillin V, is a narrow-spectrum beta-lactam antibiotic of the penicillin class, mainly active against Gram-positive bacteria. It is approved and commonly used today for the treatment of mild to moderate infections including streptococcal pharyngitis, tonsillitis, and some dental infections, generally administered orally due to its acid stability.
Pharmacokinetic parameters in healthy adult volunteers after oral administration.
Rawson, TM, et al., & Holmes, AH (2021). Exploring the Pharmacokinetics of Phenoxymethylpenicillin (Penicillin-V) in Adults: A Healthy Volunteer Study. Open forum infectious diseases 8(12) ofab573–None. DOI:10.1093/ofid/ofab573 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34934774
Langtry, HD, & Balfour, JA (1998). Azithromycin. A review of its use in paediatric infectious diseases. Drugs 56(2) 273–297. DOI:10.2165/00003495-199856020-00014 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9711451
Rawson, TM, et al., & Holmes, AH (2019). Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. The Lancet. Digital health 1(7) e335–e343. DOI:10.1016/S2589-7500(19)30131-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33323208