.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CR03_TicarcillinAndBetaLactam.TicarcillinAndBetaLactam .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01C_BetaLactamAntibacterialsPenicillins.J01CR03_TicarcillinAndBetaLactam.TicarcillinAndBetaLactam| name: | TicarcillinAndBetaLactamaseInhibitor |
| ATC code: | J01CR03 | route: | intravenous |
| n-compartments | 2 |
Ticarcillin is a broad-spectrum penicillin antibiotic that is primarily used in combination with a beta-lactamase inhibitor (typically clavulanic acid) to extend its activity against beta-lactamase-producing organisms. The combination is indicated for the treatment of various serious bacterial infections, including lower respiratory tract, urinary tract, intra-abdominal, and gynecological infections. In many countries, this formulation has been discontinued or is used less commonly today due to the development of newer agents.
Pharmacokinetic estimates for ticarcillin in combination with clavulanic acid in healthy adults, intravenous administration. Data are estimated from historical single-dose studies and reviews, as no recent publications with detailed compartmental PK parameters are available.