name: | Cefadroxil |
ATC code: | J01DB05 | route: | oral |
n-compartments | 1 |
Cefadroxil is an orally administered first-generation cephalosporin antibiotic approved for the treatment of susceptible bacterial infections, including skin and soft tissue infections, urinary tract infections, and pharyngitis/tonsillitis. It is widely used and remains approved for clinical use in many countries.
Pharmacokinetic parameters from healthy adult volunteers following single oral dose administration.
Haynes, AS, et al., & Fish, DN (2024). Cefadroxil and cephalexin pharmacokinetics and pharmacodynamics in children with musculoskeletal infections. Antimicrobial agents and chemotherapy 68(5) e0018224–None. DOI:10.1128/aac.00182-24 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38597672
Rahim, N, et al., & Khalique, UA (2016). Comparative bioavailability and pharmacokinetic study of Cefadroxil capsules in male healthy volunteers of Pakistan. Pakistan journal of pharmaceutical sciences 29(2) 453–459. PUBMED:https://pubmed.ncbi.nlm.nih.gov/27087092
Craft, JC, & Siepman, N (1993). Overview of the safety profile of clarithromycin suspension in pediatric patients. The Pediatric infectious disease journal 12(12 Suppl 3) S142–S147. DOI:10.1097/00006454-199312003-00009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8295816