.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01D_OtherBetaLactamAntibacterials.J01DC02_Cefuroxime.Cefuroxime_1

Information

name:Cefuroxime_1
ATC code:J01DC02_1
route:oral
n-compartments1

Cefuroxime is a second-generation cephalosporin antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria. It is used to treat various infections, including respiratory tract, urinary tract, skin and soft tissue infections. Cefuroxime is approved and widely used clinically.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers after a single oral dose of cefuroxime axetil tablet.

References

  1. Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866

  2. Bulitta, JB, et al., & Sorgel, F (2009). New semiphysiological absorption model to assess the pharmacodynamic profile of cefuroxime axetil using nonparametric and parametric population pharmacokinetics. Antimicrobial agents and chemotherapy 53(8) 3462–3471. DOI:10.1128/AAC.00054-09 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19528278

  3. Guay, DR (2000). Pharmacodynamics and pharmacokinetics of cefdinir, an oral extended spectrum cephalosporin. The Pediatric infectious disease journal 19(12 Suppl) S141–S146. DOI:10.1097/00006454-200012001-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11144395

Revisions


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