.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01D_OtherBetaLactamAntibacterials.J01DC04_Cefaclor.Cefaclor .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01D_OtherBetaLactamAntibacterials.J01DC04_Cefaclor.Cefaclor| name: | Cefaclor |
| ATC code: | J01DC04 | route: | oral |
| n-compartments | 1 |
Cefaclor is a second-generation cephalosporin antibiotic used to treat a variety of bacterial infections, including respiratory tract infections, otitis media, skin and soft tissue infections, and urinary tract infections. It is administered primarily orally and is approved for clinical use.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose administration.
Kanan, M, et al., & Hazza, A (2023). A Systematic Review on the Clinical Pharmacokinetics of Cephalexin in Healthy and Diseased Populations. Antibiotics (Basel, Switzerland) 12(9) –. DOI:10.3390/antibiotics12091402 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37760698
Chen, J, et al., & Ruan, Z (2012). Bioequivalence studies of 2 oral cefaclor capsule formulations in chinese healthy subjects. Arzneimittel-Forschung 62(3) 134–137. DOI:10.1055/s-0031-1298012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22286978
Langtry, HD, & Balfour, JA (1998). Azithromycin. A review of its use in paediatric infectious diseases. Drugs 56(2) 273–297. DOI:10.2165/00003495-199856020-00014 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9711451