.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01D_OtherBetaLactamAntibacterials.J01DD08_Cefixime.Cefixime

Information

Cefixime is a third-generation oral cephalosporin antibiotic used to treat a variety of bacterial infections including respiratory tract infections, urinary tract infections, otitis media, and gonorrhea. It is approved for clinical use in many countries and is available as oral tablets and suspensions.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects following a single oral dose.

References

1. Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866

2. Guay, DR (2000). Pharmacodynamics and pharmacokinetics of cefdinir, an oral extended spectrum cephalosporin. The Pediatric infectious disease journal 19(12 Suppl) S141–S146. DOI:10.1097/00006454-200012001-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11144395

3. Kong, FYS, et al., & Hocking, JS (2022). Optimisation of treatments for oral . BMJ open 12(11) e064782–None. DOI:10.1136/bmjopen-2022-064782 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36368750

Revisions

• 06/2025 initial generated model