.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01D_OtherBetaLactamAntibacterials.J01DH02_Meropenem.Meropenem_1

Information

name:Meropenem_1
ATC code:J01DH02_1
route:intravenous
n-compartments1

Meropenem is a broad-spectrum, beta-lactam carbapenem antibiotic used to treat severe bacterial infections, including those caused by multidrug-resistant bacteria. It is approved for use in hospital and clinical settings for conditions such as pneumonia, meningitis, intra-abdominal infections, and sepsis.

Pharmacokinetics

Pharmacokinetic parameters reported in adult patients with normal renal function after single dose.

References

  1. Ullah, S, et al., & Taubert, M (2023). Population pharmacokinetics of meropenem in patients undergoing automated peritoneal dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 43(5) 402–410. DOI:10.1177/08968608231167237 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37131320

  2. Abulfathi, AA, et al., & Svensson, EM (2021). The Population Pharmacokinetics of Meropenem in Adult Patients With Rifampicin-Sensitive Pulmonary Tuberculosis. Frontiers in pharmacology 12 637618–None. DOI:10.3389/fphar.2021.637618 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34267655

  3. Alshaer, MH, et al., & Hosmann, A (2022). Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue. Antimicrobial agents and chemotherapy 66(8) e0043822–None. DOI:10.1128/aac.00438-22 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35862739

Revisions


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