.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01EA02_Brodimoprim.Brodimoprim .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01EA02_Brodimoprim.Brodimoprim| name: | Brodimoprim |
| ATC code: | J01EA02 | route: | oral |
| n-compartments | 1 |
Brodimoprim is a synthetic diaminopyrimidine antibacterial agent related to trimethoprim. It acts as a selective bacterial dihydrofolate reductase inhibitor, used historically in the treatment of urinary tract and respiratory infections. It is not widely used or approved for clinical use today.
Reported pharmacokinetic parameters in healthy adult volunteers after oral administration.
Stockis, A, et al., & Rosillon, D (1993). Pharmacokinetics of brodimoprim in special populations. Journal of chemotherapy (Florence, Italy) 5(6) 480–487. PUBMED:https://pubmed.ncbi.nlm.nih.gov/8195841