.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01ED20_TrimethoprimAndSulfonami.TrimethoprimAndSulfonami .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01ED20_TrimethoprimAndSulfonami.TrimethoprimAndSulfonami| name: | TrimethoprimAndSulfonamidesCombinationsEGTrimethoprimSulfamethoxazole |
| ATC code: | J01ED20 | route: | oral |
| n-compartments | 1 |
This drug is a fixed combination of the antibiotics trimethoprim and sulfamethoxazole, commonly known as co-trimoxazole. It is primarily used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, gastrointestinal infections, and Pneumocystis jirovecii pneumonia. It remains an approved and commonly used antimicrobial combination worldwide.
Pharmacokinetic parameters for co-trimoxazole (trimethoprim 160 mg and sulfamethoxazole 800 mg) after single oral dosing in healthy adult volunteers (male and female, aged 18-50 years). Model parameters primarily refer to the trimethoprim component.