.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01EE03_SulfametroleAndTrimethop.SulfametroleAndTrimethop .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01E_SulfonamidesAndTrimethoprim.J01EE03_SulfametroleAndTrimethop.SulfametroleAndTrimethop| name: | SulfametroleAndTrimethoprim | |
| ATC code: | J01EE03 | route: | oral |
| compartments: | 1 | |
| dosage: | 400 | mg |
| volume of distribution: | 1.2 | L |
| clearance: | 2.4 | L/h |
| other parameters in model implementation | ||
Sulfametrole and trimethoprim is a fixed combination antibacterial drug containing the sulfonamide sulfametrole and the dihydrofolate reductase inhibitor trimethoprim. This combination is used to treat a variety of bacterial infections, including urinary and respiratory tract infections. The combination is similar in therapeutic approach to sulfamethoxazole/trimethoprim (co-trimoxazole), but is less commonly used today and is not approved in all countries.
Pharmacokinetic parameter estimates for healthy adult volunteers, oral administration.