.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01F_MacrolidesLincosamidesAndStreptogramins.J01FA10_Azithromycin.Azithromycin

Information

Azithromycin is a macrolide antibiotic used primarily for the treatment of respiratory tract, skin, and soft tissue infections due to susceptible bacteria. It is also indicated for some sexually transmitted infections and is widely prescribed due to its long half-life and broad-spectrum activity. Azithromycin is approved for clinical use worldwide.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers after single 500 mg oral dose.

References

1. Unemo, M, et al., & Dillon, JR (2019). Gonorrhoea. Nature reviews. Disease primers 5(1) 79–None. DOI:10.1038/s41572-019-0128-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31754194

2. Zhang, XY, et al., & Lu, W (2010). Population pharmacokinetics study of azithromycin oral formulations using NONMEM. International journal of clinical pharmacology and therapeutics 48(10) 662–669. DOI:10.5414/cpp48662 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20875372

3. Zhao, Q, et al., & Mould, DR (2014). Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed-dose azithromycin and chloroquine combination tablets. Malaria journal 13 36–None. DOI:10.1186/1475-2875-13-36 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24472224

Revisions

• 06/2025 initial generated model