.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01M_QuinoloneAntibacterials.J01MA01_Ofloxacin.Ofloxacin

Information

name:Ofloxacin
ATC code:J01MA01
route:oral
n-compartments2

Ofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and sexually transmitted diseases. It is FDA-approved and is commonly used in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after a single oral dose.

References

  1. Jaruratanasirikul, S, et al., & Samaeng, M (2018). Population Pharmacokinetics and Pharmacodynamics Modeling of Oral Levofloxacin. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 99(8) 886–892. PUBMED:https://pubmed.ncbi.nlm.nih.gov/29947489

  2. Stambaugh, JJ, et al., & Peloquin, CA (2002). Ofloxacin population pharmacokinetics in patients with tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 6(6) 503–509. DOI:10.5588/09640569513011 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12068983

  3. Zhang, J, et al., & Zhang, YY (2009). Population pharmacokinetics of oral levofloxacin 500 mg once-daily dosage in community-acquired lower respiratory tract infections: results of a prospective multicenter study in China. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 15(5) 293–300. DOI:10.1007/s10156-009-0714-8 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19856067

Revisions


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