.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01M_QuinoloneAntibacterials.J01MA02_Ciprofloxacin.Ciprofloxacin .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01M_QuinoloneAntibacterials.J01MA02_Ciprofloxacin.Ciprofloxacin| name: | Ciprofloxacin |
| ATC code: | J01MA02 | route: | oral |
| n-compartments | 2 |
Ciprofloxacin is a second-generation fluoroquinolone antibiotic used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, and skin infections. It is approved for use in adults and in selected pediatric cases for specific infections. Ciprofloxacin is generally administered orally or intravenously.
Pharmacokinetic parameters in healthy adult volunteers after single oral dose.
Hirt, D, et al., & Benaboud, S (2021). Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens. European journal of clinical pharmacology 77(11) 1687–1695. DOI:10.1007/s00228-021-03174-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34160669
Zahr, N, et al., & Funck-Brentano, C (2021). Ciprofloxacin population pharmacokinetics during long-term treatment of osteoarticular infections. The Journal of antimicrobial chemotherapy 76(11) 2906–2913. DOI:10.1093/jac/dkab275 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34363656
Junkert, AM, et al., & Pontarolo, R (2024). Pharmacokinetics of oral ciprofloxacin in adult patients: A scoping review. British journal of clinical pharmacology 90(2) 528–547. DOI:10.1111/bcp.15933 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37850318