.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01M_QuinoloneAntibacterials.J01MA19_Garenoxacin.Garenoxacin

Information

Garenoxacin is an oral des-fluoroquinolone antibiotic formerly used to treat bacterial infections, particularly respiratory and urinary tract infections. It demonstrates activity against a broad spectrum of Gram-positive and Gram-negative bacteria. Garenoxacin was approved for use in some countries (e.g., Japan), but is not currently approved in the United States or the European Union.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adult subjects after oral administration.

References

1. Fukuda, Y, et al., & Nomura, N (2012). In vitro pharmacodynamic evaluation of garenoxacin against quinolone-resistant Streptococcus pneumoniae. International journal of antimicrobial agents 39(2) 163–167. DOI:10.1016/j.ijantimicag.2011.09.021 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22088660

2. Ohsaki, Y, et al., & Fujiuchi, S (2010). Pharmacokinetics of garenoxacin in elderly patients with respiratory tract infections. International journal of antimicrobial agents 35(6) 603–605. DOI:10.1016/j.ijantimicag.2010.01.020 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20207522

Revisions

• 06/2025 initial generated model