name: | Nemonoxacin |
ATC code: | J01MB08 | route: | orally |
n-compartments | 2 |
Nemonoxacin is a non-fluorinated quinolone antibiotic, used for the treatment of community-acquired pneumonia and other infections caused by susceptible bacteria. It is approved for clinical use in certain countries primarily in Asia.
Pharmacokinetic parameters in healthy adult volunteers following oral administration.
Guo, B, et al., & Zhang, J (2012). Safety and clinical pharmacokinetics of nemonoxacin, a novel non-fluorinated quinolone, in healthy Chinese volunteers following single and multiple oral doses. Clinical drug investigation 32(7) 475–486. DOI:10.2165/11632780-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22650326
Zhao, C, et al., & Tian, J (2018). Effects of Nemonoxacin on Thorough ECG QT/QTc Interval: A Randomized, Placebo- and Positive-controlled Crossover Study in Healthy Chinese Adults. Clinical therapeutics 40(6) 983–992. DOI:10.1016/j.clinthera.2018.04.014 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29803534
Zhang, YF, et al., & Zhong, DF (2014). Effects of an Al(3+)- and Mg(2+)-containing antacid, ferrous sulfate, and calcium carbonate on the absorption of nemonoxacin (TG-873870) in healthy Chinese volunteers. Acta pharmacologica Sinica 35(12) 1586–1592. DOI:10.1038/aps.2014.95 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25327812