.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J01R_CombinationsOfAntibacterials.J01RA01_PenicillinsCombinationsW.PenicillinsCombinationsW

Information

name:PenicillinsCombinationsWithOtherAntibacterials
ATC code:J01RA01
route:intravenous
n-compartments1

Penicillins, combinations with other antibacterials (ATC J01RA01) include formulations that combine penicillin antibiotics with other antibacterial agents, often to broaden the antibacterial spectrum or mitigate resistance. These combinations are used to treat a variety of bacterial infections, including respiratory, urinary tract, and soft tissue infections. While individual agents may still be used, some specific combinations have fallen out of favor due to resistance patterns or the development of newer antibiotics.

Pharmacokinetics

Estimated typical adult values for a standard intravenous dose; no direct pharmacokinetic studies specific to penicillins, combinations with other antibacterials (J01RA01) found.

References

  1. Zhanel, GG, et al., & Karlowsky, JA (2019). Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli. Drugs 79(3) 271–289. DOI:10.1007/s40265-019-1055-2 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30712199

  2. Cho, JC, et al., & Estrada, SJ (2015). Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination. Pharmacotherapy 35(7) 701–715. DOI:10.1002/phar.1609 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26133315

  3. Haeseker, M, et al., & Verbon, A (2014). Is the standard dose of amoxicillin-clavulanic acid sufficient?. BMC pharmacology & toxicology 15 38–None. DOI:10.1186/2050-6511-15-38 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25047044

Revisions


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