name: | AmphotericinB |
ATC code: | J02AA01 | route: | intravenous |
n-compartments | 2 |
Amphotericin B is a polyene antifungal medication used primarily for the treatment of life-threatening systemic fungal infections. It acts by binding to ergosterol in fungal cell membranes, causing cell death. It is approved and widely used, particularly for severe infections caused by Candida, Aspergillus, and Cryptococcus species.
Pharmacokinetic parameters reported for adult patients (both sexes) treated for systemic fungal infections by intravenous administration of amphotericin B deoxycholate.
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