.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J02A_AntimycoticsForSystemicUse.J02AC02_Itraconazole.Itraconazole

Information

name:Itraconazole
ATC code:J02AC02
route:oral
n-compartments2

Itraconazole is a triazole antifungal agent used for the treatment of various fungal infections including those caused by Aspergillus, Candida, and dermatophytes. It is FDA-approved and commonly used for systemic mycoses and onychomycosis.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following a single oral dose of 200 mg capsule under fasting conditions.

References

  1. Sánchez, CR, et al., & Papich, MG (2019). Population pharmacokinetics of itraconazole solution after a single oral administration in captive lesser flamingos (Phoeniconaias minor). Journal of veterinary pharmacology and therapeutics 42(1) 1–6. DOI:10.1111/jvp.12721 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30302773

  2. Willems, L, et al., & de Beule, K (2001). Itraconazole oral solution and intravenous formulations: a review of pharmacokinetics and pharmacodynamics. Journal of clinical pharmacy and therapeutics 26(3) 159–169. DOI:10.1046/j.1365-2710.2001.00338.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/11422598

  3. Junkert, AM, et al., & Pontarolo, R (2024). Pharmacokinetics of oral ciprofloxacin in adult patients: A scoping review. British journal of clinical pharmacology 90(2) 528–547. DOI:10.1111/bcp.15933 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37850318

Revisions


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