.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AA03_CalciumAminosalicylate.CalciumAminosalicylate .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AA03_CalciumAminosalicylate.CalciumAminosalicylate| name: | CalciumAminosalicylate | |
| ATC code: | J04AA03 | route: | oral |
| compartments: | 1 | |
| dosage: | 4000 | mg |
| volume of distribution: | 11 | L |
| clearance: | 7 | L/h |
| other parameters in model implementation | ||
Calcium aminosalicylate, also known as calcium para-aminosalicylate, is a salt form of para-aminosalicylic acid (PAS). It is an antibacterial agent historically used as a second-line drug in the treatment of tuberculosis, particularly for strains resistant to first-line agents. Its use has largely declined due to the development of more effective and better-tolerated therapies.
Due to the lack of recent published pharmacokinetic (PK) studies specific to calcium aminosalicylate, PK parameters are estimated based on older data for para-aminosalicylic acid and its salts in adult subjects receiving oral doses.