.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AD01_Protionamide.Protionamide .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AD01_Protionamide.Protionamide| name: | Protionamide | |
| ATC code: | J04AD01 | route: | oral |
| compartments: | 1 | |
| dosage: | 250 | mg |
| volume of distribution: | 1.2 | L |
| clearance: | 75 | L/h |
| other parameters in model implementation | ||
Protionamide is a thioamide antibiotic related structurally to ethionamide, used primarily as a second-line agent for the treatment of multidrug-resistant tuberculosis (MDR-TB) and some non-tuberculous mycobacterial infections. It is not widely available in all countries and is not a first-line antituberculous drug.
Estimated pharmacokinetic parameters for an average adult patient based on class similarity to ethionamide (due to lack of direct published data for protionamide). Assumed oral administration in adults.