.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AK02_Ethambutol.Ethambutol .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J04A_DrugsForTreatmentOfTuberculosis.J04AK02_Ethambutol.Ethambutol| name: | Ethambutol |
| ATC code: | J04AK02 | route: | oral |
| n-compartments | 1 |
Ethambutol is an oral antimycobacterial agent primarily used in the treatment of tuberculosis, usually in combination with other antituberculosis agents. It is approved and widely used today and works by inhibiting cell wall synthesis in Mycobacterium species.
Pharmacokinetic parameters reported for healthy adult volunteers after oral administration.
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Chen, C, et al., & Simonsson, US (2016). Population pharmacokinetics, optimised design and sample size determination for rifampicin, isoniazid, ethambutol and pyrazinamide in the mouse. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 93 319–333. DOI:10.1016/j.ejps.2016.07.017 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27473307