.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J05A_DirectActingAntivirals.J05AB01_Aciclovir.Aciclovir_1

Information

name:Aciclovir_1
ATC code:J05AB01_1
route:intravenous
n-compartments2

Aciclovir is an antiviral drug used for treatment and prevention of herpesviridae infections, including HSV and VZV, by inhibiting viral DNA replication. It is widely approved and used.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.

References

  1. O'Brien, JJ, & Campoli-Richards, DM (1989). Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy. Drugs 37(3) 233–309. DOI:10.2165/00003495-198937030-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2653790

  2. Noble, S, & Faulds, D (1998). Ganciclovir. An update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs 56(1) 115–146. DOI:10.2165/00003495-199856010-00012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9664203

Revisions

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