.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J05A_DirectActingAntivirals.J05AB06_Ganciclovir.Ganciclovir_1

Information

name:Ganciclovir_1
ATC code:J05AB06_1
route:intravenous
compartments:2
dosage:350mg
volume of distribution:0.67L
clearance:3.8mL/min/kg
other parameters in model implementation

Ganciclovir is an antiviral medication used for the treatment and prevention of cytomegalovirus (CMV) infections in immunocompromised individuals. It remains an essential antiviral for this indication.

Pharmacokinetics

Population pharmacokinetics model in renal transplant recipients; intravenous administration of 5 mg/kg.

References

  1. Nguyen, T, et al., & Hirt, D (2021). Population Pharmacokinetics of Intravenous Ganciclovir and Oral Valganciclovir in a Pediatric Population To Optimize Dosing Regimens. Antimicrobial agents and chemotherapy 65(3) –. DOI:10.1128/AAC.02254-20 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33318012

  2. Selby, PR, et al., & Roberts, JA (2023). Population Pharmacokinetics of Ganciclovir in Allogeneic Hematopoietic Stem Cell Transplant Patients. Antimicrobial agents and chemotherapy 67(3) e0155022–None. DOI:10.1128/aac.01550-22 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36815858

  3. Li, S, et al., & Wang, Y (2020). Population Pharmacokinetics and Dose Optimization of Ganciclovir in Critically Ill Children. Frontiers in pharmacology 11 614164–None. DOI:10.3389/fphar.2020.614164 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33536921

Revisions


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