name: | Didanosine |
ATC code: | J05AF02 | route: | oral |
n-compartments | 1 |
Didanosine is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment of human immunodeficiency virus (HIV) infection. It inhibits viral replication by interfering with viral reverse transcriptase. Didanosine was widely used in HIV therapy but its use has declined due to the availability of better-tolerated alternatives and concerns about toxicity. It is still used today in some settings, although less frequently.
Pharmacokinetic parameters reported for adult HIV-infected patients following single oral doses of didanosine 200 mg (fasting state).
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