name: | Ribavirin |
ATC code: | J05AP01 | route: | oral |
n-compartments | 2 |
Ribavirin is a synthetic nucleoside analog with broad-spectrum antiviral activity. It is primarily used for the treatment of hepatitis C in combination with other drugs and for severe respiratory syncytial virus (RSV) infections in certain populations. Ribavirin is approved for use in combination therapy for hepatitis C virus (HCV) infection and is also used off-label for other viral infections.
Pharmacokinetic parameters reported in healthy adult males after single oral dose.
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Mensing, S, et al., & Dutta, S (2016). Population Pharmacokinetics of Paritaprevir, Ombitasvir, Dasabuvir, Ritonavir, and Ribavirin in Patients with Hepatitis C Virus Genotype 1 Infection: Combined Analysis from 9 Phase 1b/2 Studies. The AAPS journal 18(1) 270–280. DOI:10.1208/s12248-015-9846-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26597291
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