name: | ZidovudineAndLamivudine |
ATC code: | J05AR01 | route: | oral |
n-compartments | 1 |
Zidovudine and lamivudine are antiretroviral medications combined to treat HIV-1 infection. Both are nucleoside reverse transcriptase inhibitors (NRTIs) and are used as a backbone in combination antiretroviral therapy (ART). The fixed-dose combination is approved and widely used today for the management of HIV infection.
Pharmacokinetic parameters for zidovudine and lamivudine following oral administration in healthy adult volunteers.
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