name: | Bulevirtide |
ATC code: | J05AX28 | route: | subcutaneous |
n-compartments | 1 |
Bulevirtide is an entry inhibitor used for the treatment of chronic hepatitis B and D virus infection. It acts by binding to and blocking the sodium taurocholate co-transporting polypeptide (NTCP) receptor on hepatocytes, thereby preventing viral entry. Bulevirtide is approved for medical use in the European Union for chronic hepatitis D infection in adults with compensated liver disease.
Pharmacokinetics in healthy adult subjects following subcutaneous administration; population pharmacokinetic modeling.